| # | Title | Journal | Year | Citations |
|---|
| 1 | The PRISMA 2020 statement: an updated guideline for reporting systematic reviews | BMJ, The | 2021 | 26,066 |
| 2 | The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) | JAMA - Journal of the American Medical Association | 2016 | 16,554 |
| 3 | Initial conditions and moment restrictions in dynamic panel data models | Journal of Econometrics | 1998 | 15,755 |
| 4 | Rethinking the Inception Architecture for Computer Vision | Journal of Econometrics | 2016 | 14,916 |
| 5 | The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease | Alzheimer's and Dementia | 2011 | 12,681 |
| 6 | The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments | Clinical Chemistry | 2009 | 12,487 |
| 7 | Nonlinear Dimensionality Reduction by Locally Linear Embedding | Science | 2000 | 12,086 |
| 8 | DeepLab: Semantic Image Segmentation with Deep Convolutional Nets, Atrous Convolution, and Fully Connected CRFs | IEEE Transactions on Pattern Analysis and Machine Intelligence | 2018 | 11,963 |
| 9 | PAML 4: Phylogenetic Analysis by Maximum Likelihood | Molecular Biology and Evolution | 2007 | 11,130 |
| 10 | The Hallmarks of Aging | Cell | 2013 | 10,992 |
| 11 | RoB 2: a revised tool for assessing risk of bias in randomised trials | BMJ: British Medical Journal | 2019 | 10,984 |
| 12 | Astropy: A community Python package for astronomy | Astronomy and Astrophysics | 2013 | 8,416 |
| 13 | Planck2015 results | Astronomy and Astrophysics | 2016 | 8,344 |
| 14 | COVID-19: consider cytokine storm syndromes and immunosuppression | Lancet, The | 2020 | 7,677 |
| 15 | The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease | Alzheimer's and Dementia | 2011 | 7,498 |
| 16 | Developing and evaluating complex interventions: the new Medical Research Council guidance | BMJ, The | 2008 | 7,454 |
| 17 | Planetary boundaries: Guiding human development on a changing planet | Science | 2015 | 7,124 |
| 18 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 19 | The behaviour change wheel: A new method for characterising and designing behaviour change interventions | Implementation Science | 2011 | 6,856 |
| 20 | Tract-based spatial statistics: Voxelwise analysis of multi-subject diffusion data | NeuroImage | 2006 | 5,755 |
| 21 | Rho GTPases and the Actin Cytoskeleton | Science | 1998 | 5,721 |
| 22 | Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide | BMJ, The | 2014 | 5,661 |
| 23 | The Logic of Animal Conflict | Nature | 1973 | 5,362 |
| 24 | The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat | Brain Research | 1971 | 5,261 |
| 25 | Diffusion of Innovations in Service Organizations: Systematic Review and Recommendations | Milbank Quarterly | 2004 | 5,181 |
| 26 | Applications of magnetic nanoparticles in biomedicine | Journal Physics D: Applied Physics | 2003 | 5,148 |
| 27 | The Behavior Change Technique Taxonomy (v1) of 93 Hierarchically Clustered Techniques: Building an International Consensus for the Reporting of Behavior Change Interventions | Annals of Behavioral Medicine | 2013 | 4,927 |
| 28 | The free-energy principle: a unified brain theory? | Nature Reviews Neuroscience | 2010 | 4,902 |
| 29 | The rapid generation of mutation data matrices from protein sequences | Bioinformatics | 1992 | 4,891 |
| 30 | AQUA and PROCHECK-NMR: Programs for checking the quality of protein structures solved by NMR | Journal of Biomolecular NMR | 1996 | 4,736 |
| 31 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 32 | Dementia prevention, intervention, and care: 2020 report of the Lancet Commission | Lancet, The | 2020 | 4,658 |
| 33 | Updated guidance for trusted systematic reviews: a new edition of the Cochrane Handbook for Systematic Reviews of Interventions | The Cochrane Library | 2019 | 4,644 |
| 34 | Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines | Immunity | 2014 | 4,638 |
| 35 | Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria | Lancet Neurology, The | 2018 | 4,605 |
| 36 | The socio-economic implications of the coronavirus pandemic (COVID-19): A review | International Journal of Surgery | 2020 | 4,299 |
| 37 | Rho GTPases in cell biology | Nature | 2002 | 4,288 |
| 38 | Dementia prevention, intervention, and care | Lancet, The | 2017 | 4,228 |
| 39 | A Voxel-Based Morphometric Study of Ageing in 465 Normal Adult Human Brains | NeuroImage | 2001 | 4,189 |
| 40 | Wound Healing--Aiming for Perfect Skin Regeneration | Science | 1997 | 4,155 |
| 41 | Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science | Lancet Psychiatry,the | 2020 | 4,086 |
| 42 | Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia | Cell | 1995 | 4,053 |
| 43 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 | Cell Death and Differentiation | 2018 | 4,036 |
| 44 | The resurgence of platinum-based cancer chemotherapy | Nature Reviews Cancer | 2007 | 3,971 |
| 45 | Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration | Lancet Neurology, The | 2013 | 3,919 |
| 46 | World Health Organization declares global emergency: A review of the 2019 novel coronavirus (COVID-19) | International Journal of Surgery | 2020 | 3,919 |
| 47 | Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK | Lancet, The | 2021 | 3,887 |
| 48 | Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial | Lancet, The | 2005 | 3,840 |
| 49 | Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus | Arthritis and Rheumatism | 2012 | 3,838 |
| 50 | A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD | Neuron | 2011 | 3,833 |
