| # | Title | Journal | Year | Citations |
|---|
| 1 | Analysis of protein-coding genetic variation in 60,706 humans | Nature | 2016 | 9,051 |
| 2 | Planck2015 results | Astronomy and Astrophysics | 2016 | 8,344 |
| 3 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 4 | EFFECTS OF BIODIVERSITY ON ECOSYSTEM FUNCTIONING: A CONSENSUS OF CURRENT KNOWLEDGE | Ecological Monographs | 2005 | 5,856 |
| 5 | A Large and Persistent Carbon Sink in the World’s Forests | Science | 2011 | 5,393 |
| 6 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 7 | Positive matrix factorization: A non-negative factor model with optimal utilization of error estimates of data values | Environmetrics | 1994 | 4,492 |
| 8 | Nuclear ribosomal internal transcribed spacer (ITS) region as a universal DNA barcode marker for Fungi | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 4,012 |
| 9 | Biological properties of extracellular vesicles and their physiological functions | Journal of Extracellular Vesicles | 2015 | 3,973 |
| 10 | The Genome of Black Cottonwood, Populus trichocarpa (Torr. & Gray) | Science | 2006 | 3,945 |
| 11 | Helsinki Heart Study: Primary-Prevention Trial with Gemfibrozil in Middle-Aged Men with Dyslipidemia | New England Journal of Medicine | 1987 | 3,839 |
| 12 | A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD | Neuron | 2011 | 3,833 |
| 13 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,823 |
| 14 | Environmental and Heritable Factors in the Causation of Cancer — Analyses of Cohorts of Twins from Sweden, Denmark, and Finland | New England Journal of Medicine | 2000 | 3,583 |
| 15 | Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes | New England Journal of Medicine | 2014 | 3,474 |
| 16 | Dali server: conservation mapping in 3D | Nucleic Acids Research | 2010 | 3,433 |
| 17 | Evolution of Organic Aerosols in the Atmosphere | Science | 2009 | 3,374 |
| 18 | Biological, clinical and population relevance of 95 loci for blood lipids | Nature | 2010 | 3,249 |
| 19 | Europe-wide reduction in primary productivity caused by the heat and drought in 2003 | Nature | 2005 | 3,245 |
| 20 | Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II) | Lancet, The | 1998 | 3,216 |
| 21 | Review of Particle Physics | Progress of Theoretical and Experimental Physics | 2020 | 3,177 |
| 22 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 23 | Antioxidants, Oxidative Damage and Oxygen Deprivation Stress: a Review | Annals of Botany | 2003 | 3,040 |
| 24 | Towards a unified paradigm for sequence‐based identification of fungi | Molecular Ecology | 2013 | 2,997 |
| 25 | The N1 Wave of the Human Electric and Magnetic Response to Sound: A Review and an Analysis of the Component Structure | Psychophysiology | 1987 | 2,857 |
| 26 | Structural Defects in Graphene | ACS Nano | 2011 | 2,818 |
| 27 | On the separation of net ecosystem exchange into assimilation and ecosystem respiration: review and improved algorithm | Global Change Biology | 2005 | 2,778 |
| 28 | Solubilization of membranes by detergents | BBA - Biomembranes | 1975 | 2,762 |
| 29 | Antioxidant Activity of Plant Extracts Containing Phenolic Compounds | Journal of Agricultural and Food Chemistry | 1999 | 2,740 |
| 30 | Discovery and refinement of loci associated with lipid levels | Nature Genetics | 2013 | 2,641 |
| 31 | Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index | Nature Genetics | 2010 | 2,634 |
| 32 | “Effective” Number of Parties | Comparative Political Studies | 1979 | 2,630 |
| 33 | Genome-Wide Association Analysis Identifies Loci for Type 2 Diabetes and Triglyceride Levels | Science | 2007 | 2,623 |
| 34 | Clues to the pathogenesis of familial colorectal cancer | Science | 1993 | 2,563 |
| 35 | Minuit - a system for function minimization and analysis of the parameter errors and correlations | Computer Physics Communications | 1975 | 2,478 |
| 36 | A reference panel of 64,976 haplotypes for genotype imputation | Nature Genetics | 2016 | 2,421 |
| 37 | A unified classification system for eukaryotic transposable elements | Nature Reviews Genetics | 2007 | 2,396 |
| 38 | Independent Component Analysis | Nature Reviews Genetics | 2004 | 2,368 |
| 39 | Review of particle properties | Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics | 1988 | 2,340 |
| 40 | Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel | European Heart Journal | 2017 | 2,292 |
| 41 | Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome | Gastroenterology | 2012 | 2,287 |
| 42 | Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer | Cell | 1993 | 2,195 |
| 43 | The mismatch negativity (MMN) in basic research of central auditory processing: A review | Clinical Neurophysiology | 2007 | 2,188 |
| 44 | Animals in a bacterial world, a new imperative for the life sciences | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 2,181 |
| 45 | Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: Consensus Statement of the European Atherosclerosis Society | European Heart Journal | 2013 | 2,132 |
| 46 | The repertoire of mutational signatures in human cancer | Nature | 2020 | 2,104 |
| 47 | A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease | Nature Genetics | 2015 | 2,054 |
| 48 | The Human Transcription Factors | Cell | 2018 | 2,048 |
| 49 | New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk | Nature Genetics | 2010 | 1,982 |
| 50 | Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease | Nature | 2003 | 1,980 |
