| # | Title | Journal | Year | Citations |
|---|
| 1 | “Mini-mental state” | Journal of Psychiatric Research | 1975 | 77,621 |
| 2 | Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries | Ca-A Cancer Journal for Clinicians | 2018 | 62,121 |
| 3 | A Revised Medium for Rapid Growth and Bio Assays with Tobacco Tissue Cultures | Physiologia Plantarum | 1962 | 56,749 |
| 4 | The Measurement of Observer Agreement for Categorical Data | Biometrics | 1977 | 55,540 |
| 5 | Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries | Ca-A Cancer Journal for Clinicians | 2021 | 52,977 |
| 6 | Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement | PLoS Medicine | 2009 | 50,671 |
| 7 | Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays | Journal of Immunological Methods | 1983 | 47,133 |
| 8 | A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation | Journal of Chronic Diseases | 1987 | 40,131 |
| 9 | STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT | Lancet, The | 1986 | 39,917 |
| 10 | A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION | Canadian Journal of Biochemistry and Physiology | 1959 | 39,151 |
| 11 | Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks | Genome Research | 2003 | 37,062 |
| 12 | The Hospital Anxiety and Depression Scale | Acta Psychiatrica Scandinavica | 1983 | 36,914 |
| 13 | Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China | Lancet, The | 2020 | 36,800 |
| 14 | Meta-analysis in clinical trials | Contemporary Clinical Trials | 1986 | 33,020 |
| 15 | Research electronic data capture (REDCap)—A metadata-driven methodology and workflow process for providing translational research informatics support | Journal of Biomedical Informatics | 2009 | 32,739 |
| 16 | The assessment and analysis of handedness: The Edinburgh inventory | Neuropsychologia | 1971 | 32,207 |
| 17 | Global cancer statistics | Ca-A Cancer Journal for Clinicians | 2011 | 32,172 |
| 18 | An Inventory for Measuring Depression | Archives of General Psychiatry | 1961 | 30,857 |
| 19 | The MOS 36-ltem Short-Form Health Survey (SF-36) | Medical Care | 1992 | 29,313 |
| 20 | The PHQ-9 | Journal of General Internal Medicine | 2001 | 29,194 |
| 21 | Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man | Diabetologia | 1985 | 27,582 |
| 22 | A RATING SCALE FOR DEPRESSION | Journal of Neurology, Neurosurgery and Psychiatry | 1960 | 27,271 |
| 23 | Three Approaches to Qualitative Content Analysis | Qualitative Health Research | 2005 | 27,239 |
| 24 | Clinical diagnosis of Alzheimer's disease | Neurology | 1984 | 27,121 |
| 25 | Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge | Clinical Chemistry | 1972 | 26,892 |
| 26 | Quantifying heterogeneity in a meta-analysis | Statistics in Medicine | 2002 | 26,845 |
| 27 | PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses | American Journal of Human Genetics | 2007 | 26,761 |
| 28 | Coot: model-building tools for molecular graphics | Acta Crystallographica Section D: Biological Crystallography | 2004 | 26,736 |
| 29 | A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION | Canadian Journal of Biochemistry and Physiology | 1959 | 25,451 |
| 30 | Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) | JAMA - Journal of the American Medical Association | 2001 | 24,499 |
| 31 | Classification of Surgical Complications | Annals of Surgery | 2004 | 24,015 |
| 32 | Global cancer statistics, 2012 | Ca-A Cancer Journal for Clinicians | 2015 | 23,881 |
| 33 | Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012 | International Journal of Cancer | 2015 | 23,615 |
| 34 | Self-determination theory and the facilitation of intrinsic motivation, social development, and well-being. | American Psychologist | 2000 | 23,552 |
| 35 | A new and rapid colorimetric determination of acetylcholinesterase activity | Biochemical Pharmacology | 1961 | 23,305 |
| 36 | The Pittsburgh sleep quality index: A new instrument for psychiatric practice and research | Psychiatry Research | 1989 | 23,254 |
| 37 | Features and development of Coot | Acta Crystallographica Section D: Biological Crystallography | 2010 | 22,799 |
| 38 | The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus | New England Journal of Medicine | 1993 | 22,781 |
| 39 | Clinical Characteristics of Coronavirus Disease 2019 in China | New England Journal of Medicine | 2020 | 22,372 |
| 40 | New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1) | European Journal of Cancer | 2009 | 21,739 |
| 41 | Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study | Lancet, The | 2020 | 21,698 |
| 42 | A Novel Coronavirus from Patients with Pneumonia in China, 2019 | New England Journal of Medicine | 2020 | 21,542 |
| 43 | The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data | Genome Research | 2010 | 21,358 |
| 44 | The Satisfaction With Life Scale | Journal of Personality Assessment | 1985 | 21,076 |
| 45 | A Global Measure of Perceived Stress | Journal of Health and Social Behavior | 1983 | 21,013 |
| 46 | PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer | Breast Care | 2016 | 20,872 |
| 47 | PHENIX: a comprehensive Python-based system for macromolecular structure solution | Acta Crystallographica Section D: Biological Crystallography | 2010 | 20,564 |
| 48 | Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement | Annals of Internal Medicine | 2009 | 20,458 |
| 49 | Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology | Genetics in Medicine | 2015 | 20,455 |
| 50 | Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups | International Journal for Quality in Health Care | 2007 | 20,392 |
| 51 | Atherosclerosis — An Inflammatory Disease | New England Journal of Medicine | 1999 | 19,732 |
| 52 | Magnesium Replacement Improves the Metabolic Profile in Obese and Pre-Diabetic Patients with Mild-to-Moderate Chronic Kidney Disease: A 3-Month, Randomised, Double-Blind, Placebo-Controlled Study | Kidney and Blood Pressure Research | 2017 | 19,694 |
| 53 | A New Equation to Estimate Glomerular Filtration Rate | Annals of Internal Medicine | 2009 | 19,025 |
| 54 | A Brief Measure for Assessing Generalized Anxiety Disorder | Archives of Internal Medicine | 2006 | 18,596 |
| 55 | The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis | Arthritis and Rheumatism | 1988 | 18,339 |
| 56 | Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33) | Lancet, The | 1998 | 18,169 |
| 57 | The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood PressureThe JNC 7 Report | JAMA - Journal of the American Medical Association | 2003 | 18,097 |
| 58 | Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China | JAMA - Journal of the American Medical Association | 2020 | 18,030 |
| 59 | Antioxidant activity applying an improved ABTS radical cation decolorization assay | Free Radical Biology and Medicine | 1999 | 17,909 |
| 60 | The meaning and use of the area under a receiver operating characteristic (ROC) curve. | Radiology | 1982 | 17,831 |
| 61 | The Positive and Negative Syndrome Scale (PANSS) for Schizophrenia | Schizophrenia Bulletin | 1987 | 17,788 |
| 62 | World Medical Association Declaration of Helsinki | JAMA - Journal of the American Medical Association | 2013 | 17,754 |
| 63 | Cancer statistics, 2019 | Ca-A Cancer Journal for Clinicians | 2019 | 17,512 |
| 64 | Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma | New England Journal of Medicine | 2005 | 17,395 |
| 65 | Meta-analysis of Observational Studies in EpidemiologyA Proposal for Reporting | JAMA - Journal of the American Medical Association | 2000 | 17,346 |
| 66 | Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches | Pflugers Archiv European Journal of Physiology | 1981 | 17,126 |
| 67 | Multiple Range and Multiple F Tests | Biometrics | 1955 | 17,123 |
| 68 | Frailty in Older Adults: Evidence for a Phenotype | Journals of Gerontology - Series A Biological Sciences and Medical Sciences | 2001 | 16,817 |
| 69 | Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors | Gene | 1985 | 16,607 |
| 70 | Comparing the Areas under Two or More Correlated Receiver Operating Characteristic Curves: A Nonparametric Approach | Biometrics | 1988 | 16,564 |
| 71 | Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement | Systematic Reviews | 2015 | 16,556 |
| 72 | The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) | JAMA - Journal of the American Medical Association | 2016 | 16,554 |
| 73 | The Montreal Cognitive Assessment, MoCA: A Brief Screening Tool For Mild Cognitive Impairment | Journal of the American Geriatrics Society | 2005 | 16,505 |
| 74 | Cancer statistics, 2020 | Ca-A Cancer Journal for Clinicians | 2020 | 16,450 |
| 75 | The measurement of observer agreement for categorical data | Biometrics | 1977 | 16,399 |
| 76 | The CCP4 suite: programs for protein crystallography | Acta Crystallographica Section D: Biological Crystallography | 1994 | 16,158 |
| 77 | Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study | Lancet, The | 2020 | 16,090 |
| 78 | Assessing the quality of reports of randomized clinical trials: Is blinding necessary? | Contemporary Clinical Trials | 1996 | 16,054 |
| 79 | Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin | New England Journal of Medicine | 2002 | 16,031 |
| 80 | Global Cancer Statistics, 2002 | Ca-A Cancer Journal for Clinicians | 2005 | 15,952 |
| 81 | APACHE II | Critical Care Medicine | 1985 | 15,512 |
| 82 | The “Golden Age” of Probiotics: A Systematic Review and Meta-Analysis of Randomized and Observational Studies in Preterm Infants | Neonatology | 2017 | 15,430 |
| 83 | PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation | Annals of Internal Medicine | 2018 | 15,209 |
| 84 | Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey Replication | Archives of General Psychiatry | 2005 | 15,111 |
| 85 | Cancer statistics, 2016 | Ca-A Cancer Journal for Clinicians | 2016 | 14,876 |
| 86 | New Guidelines to Evaluate the Response to Treatment in Solid Tumors | Journal of the National Cancer Institute | 2000 | 14,815 |
| 87 | Studies of interference in serial verbal reactions. | Journal of Experimental Psychology | 1935 | 14,787 |
| 88 | Cancer statistics, 2018 | Ca-A Cancer Journal for Clinicians | 2018 | 14,774 |
| 89 | Mapping the Margins: Intersectionality, Identity Politics, and Violence against Women of Color | Stanford Law Review | 1991 | 14,731 |
| 90 | Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination | Acta Crystallographica Section D: Biological Crystallography | 1998 | 14,711 |
| 91 | Assessment of Older People: Self-Maintaining and Instrumental Activities of Daily Living | Gerontologist, The | 1969 | 14,702 |
| 92 | Structure validation in chemical crystallography | Acta Crystallographica Section D: Biological Crystallography | 2009 | 14,659 |
| 93 | Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled Trial | JAMA - Journal of the American Medical Association | 2002 | 14,536 |
| 94 | Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008 | International Journal of Cancer | 2010 | 14,479 |
| 95 | Ventilation with Lower Tidal Volumes as Compared with Traditional Tidal Volumes for Acute Lung Injury and the Acute Respiratory Distress Syndrome | New England Journal of Medicine | 2000 | 14,454 |
| 96 | The genetical evolution of social behaviour. I | Journal of Theoretical Biology | 1964 | 14,412 |
| 97 | Cancer statistics in China, 2015 | Ca-A Cancer Journal for Clinicians | 2016 | 14,374 |
| 98 | Intensive Insulin Therapy in Critically Ill Patients | New England Journal of Medicine | 2001 | 14,320 |
| 99 | Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China | JAMA - Journal of the American Medical Association | 2020 | 14,320 |
| 100 | International Physical Activity Questionnaire: 12-Country Reliability and Validity | Medicine and Science in Sports and Exercise | 2003 | 14,285 |
