| # | Title | Journal | Year | Citations |
|---|
| 1 | Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries | Ca-A Cancer Journal for Clinicians | 2018 | 62,121 |
| 2 | Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries | Ca-A Cancer Journal for Clinicians | 2021 | 52,977 |
| 3 | Global cancer statistics | Ca-A Cancer Journal for Clinicians | 2011 | 32,172 |
| 4 | Global cancer statistics, 2012 | Ca-A Cancer Journal for Clinicians | 2015 | 23,881 |
| 5 | Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012 | International Journal of Cancer | 2015 | 23,615 |
| 6 | New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1) | European Journal of Cancer | 2009 | 21,739 |
| 7 | PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer | Breast Care | 2016 | 20,872 |
| 8 | Cancer statistics, 2019 | Ca-A Cancer Journal for Clinicians | 2019 | 17,512 |
| 9 | Cancer statistics, 2020 | Ca-A Cancer Journal for Clinicians | 2020 | 16,450 |
| 10 | Global Cancer Statistics, 2002 | Ca-A Cancer Journal for Clinicians | 2005 | 15,952 |
| 11 | Cancer statistics, 2016 | Ca-A Cancer Journal for Clinicians | 2016 | 14,876 |
| 12 | New Guidelines to Evaluate the Response to Treatment in Solid Tumors | Journal of the National Cancer Institute | 2000 | 14,815 |
| 13 | Cancer statistics, 2018 | Ca-A Cancer Journal for Clinicians | 2018 | 14,774 |
| 14 | Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008 | International Journal of Cancer | 2010 | 14,479 |
| 15 | Cancer statistics in China, 2015 | Ca-A Cancer Journal for Clinicians | 2016 | 14,374 |
| 16 | Cancer statistics, 2017 | Ca-A Cancer Journal for Clinicians | 2017 | 13,864 |
| 17 | Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement | Cytotherapy | 2006 | 13,839 |
| 18 | Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics | British Journal of Cancer | 1972 | 13,541 |
| 19 | The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data | Cancer Discovery | 2012 | 12,801 |
| 20 | The European Organization for Research and Treatment of Cancer QLQ-C30: A Quality-of-Life Instrument for Use in International Clinical Trials in Oncology | Journal of the National Cancer Institute | 1993 | 12,309 |
| 21 | Cancer Statistics, 2010 | Ca-A Cancer Journal for Clinicians | 2010 | 12,112 |
| 22 | Cancer Statistics, 2021 | Ca-A Cancer Journal for Clinicians | 2021 | 12,002 |
| 23 | Cancer statistics, 2015 | Ca-A Cancer Journal for Clinicians | 2015 | 11,344 |
| 24 | Cancer statistics, 2013 | Ca-A Cancer Journal for Clinicians | 2013 | 11,318 |
| 25 | Cancer statistics, 2014 | Ca-A Cancer Journal for Clinicians | 2014 | 10,909 |
| 26 | The blockade of immune checkpoints in cancer immunotherapy | Nature Reviews Cancer | 2012 | 10,874 |
| 27 | Cancer statistics, 2012 | Ca-A Cancer Journal for Clinicians | 2012 | 10,209 |
| 28 | Cancer statistics, 2022 | Ca-A Cancer Journal for Clinicians | 2022 | 10,001 |
| 29 | Cancer Statistics, 2008 | Ca-A Cancer Journal for Clinicians | 2008 | 9,724 |
| 30 | Statistical aspects of the analysis of data from retrospective studies of disease | Journal of the National Cancer Institute | 1959 | 9,499 |
| 31 | Cancer Statistics, 2009 | Ca-A Cancer Journal for Clinicians | 2009 | 9,422 |
| 32 | Toxicity and response criteria of the Eastern Cooperative Oncology Group | American Journal of Clinical Oncology: Cancer Clinical Trials | 1982 | 9,257 |
| 33 | Evaluation of Factors Related to Late Recurrence - Later than 10 Years after the Initial Treatment - in Primary Breast Cancer | Oncology | 2013 | 8,974 |
| 34 | Index for rating diagnostic tests | Cancer | 1950 | 8,625 |
| 35 | New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening | Journal of the National Cancer Institute | 1990 | 8,381 |
| 36 | The detection of disease clustering and a generalized regression approach | Cancer Research | 1967 | 8,008 |
| 37 | Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples | British Journal of Cancer | 1977 | 7,627 |
| 38 | Reporting results of cancer treatment | Cancer | 1981 | 7,386 |
| 39 | Cancer Statistics, 2007 | Ca-A Cancer Journal for Clinicians | 2007 | 7,103 |
| 40 | The American Joint Committee on Cancer: the 7th Edition of the AJCC Cancer Staging Manual and the Future of TNM | Annals of Surgical Oncology | 2010 | 7,085 |
| 41 | MicroRNA signatures in human cancers | Nature Reviews Cancer | 2006 | 7,008 |
| 42 | Oncomirs — microRNAs with a role in cancer | Nature Reviews Cancer | 2006 | 6,509 |
| 43 | Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial | Lancet Oncology, The | 2009 | 6,451 |
| 44 | Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1 | Cancer Cell | 2010 | 6,138 |
| 45 | Targeting HIF-1 for cancer therapy | Nature Reviews Cancer | 2003 | 6,111 |
| 46 | Normalization of Real-Time Quantitative Reverse Transcription-PCR Data: A Model-Based Variance Estimation Approach to Identify Genes Suited for Normalization, Applied to Bladder and Colon Cancer Data Sets | Cancer Research | 2004 | 5,993 |
| 47 | Epithelial–mesenchymal transitions in tumour progression | Nature Reviews Cancer | 2002 | 5,923 |
| 48 | CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2006-2010 | Neuro-Oncology | 2013 | 5,799 |
| 49 | Photodynamic therapy for cancer | Nature Reviews Cancer | 2003 | 5,585 |
| 50 | The phosphatidylinositol 3-Kinase–AKT pathway in human cancer | Nature Reviews Cancer | 2002 | 5,480 |
| 51 | Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States | Cancer Research | 2014 | 5,433 |
| 52 | New functions for the matrix metalloproteinases in cancer progression | Nature Reviews Cancer | 2002 | 5,365 |
| 53 | Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods | International Journal of Cancer | 2019 | 5,337 |
| 54 | Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. | Journal of Clinical Oncology | 1997 | 5,294 |
| 55 | Tamoxifen for Prevention of Breast Cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study | Journal of the National Cancer Institute | 1998 | 5,238 |
| 56 | Cancer Statistics, 2005 | Ca-A Cancer Journal for Clinicians | 2005 | 5,195 |
| 57 | A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs | Cancer Research | 1986 | 5,187 |
| 58 | Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial | Lancet Oncology, The | 2009 | 5,104 |
| 59 | Cancer Statistics, 2006 | Ca-A Cancer Journal for Clinicians | 2006 | 5,083 |
| 60 | The Functional Assessment of Cancer Therapy scale: development and validation of the general measure. | Journal of Clinical Oncology | 1993 | 5,004 |
| 61 | Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial | Lancet Oncology, The | 2012 | 4,943 |
| 62 | Multidrug resistance in cancer: role of ATP–dependent transporters | Nature Reviews Cancer | 2002 | 4,873 |
| 63 | Content analysis and thematic analysis: Implications for conducting a qualitative descriptive study | Australian Journal of Cancer Nursing | 2013 | 4,801 |
| 64 | Photodynamic Therapy | Journal of the National Cancer Institute | 1998 | 4,721 |
| 65 | Statistical Aspects of the Analysis of Data From Retrospective Studies of Disease | Journal of the National Cancer Institute | 0 | 4,659 |
| 66 | Signet-Ring Cell Carcinoma of the Colon: A Case Report and Review of the Literature | Case Reports in Oncology | 2015 | 4,609 |
| 67 | Hypoxia — a key regulatory factor in tumour growth | Nature Reviews Cancer | 2002 | 4,590 |
| 68 | The 2021 WHO Classification of Tumors of the Central Nervous System: a summary | Neuro-Oncology | 2021 | 4,534 |
| 69 | Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012 | European Journal of Cancer | 2013 | 4,448 |
| 70 | Cancer statistics, 2023 | Ca-A Cancer Journal for Clinicians | 2023 | 4,445 |
| 71 | Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method | Cancer Research | 2010 | 4,304 |
| 72 | Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015 | JAMA Oncology | 2017 | 4,254 |
| 73 | What Is the Evidence That Tumors Are Angiogenesis Dependent? | Journal of the National Cancer Institute | 1990 | 4,220 |
| 74 | Why do cancers have high aerobic glycolysis? | Nature Reviews Cancer | 2004 | 4,181 |
| 75 | UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses | Neoplasia | 2017 | 4,166 |
| 76 | Population Structure and Eigenanalysis | PLoS Genetics | 2006 | 4,163 |
| 77 | Cancer nanomedicine: progress, challenges and opportunities | Nature Reviews Cancer | 2017 | 4,153 |
| 78 | International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung Adenocarcinoma | Journal of Thoracic Oncology | 2011 | 4,127 |
| 79 | Final Version of 2009 AJCC Melanoma Staging and Classification | Journal of Clinical Oncology | 2009 | 4,126 |
| 80 | Cancer treatment and survivorship statistics, 2016 | Ca-A Cancer Journal for Clinicians | 2016 | 4,123 |
| 81 | Cancer nanotechnology: opportunities and challenges | Nature Reviews Cancer | 2005 | 4,111 |
| 82 | Regulation of cancer cell metabolism | Nature Reviews Cancer | 2011 | 4,100 |
| 83 | Revised Response Criteria for Malignant Lymphoma | Journal of Clinical Oncology | 2007 | 4,061 |
| 84 | TIMER: A Web Server for Comprehensive Analysis of Tumor-Infiltrating Immune Cells | Cancer Research | 2017 | 4,049 |
| 85 | HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis | Pediatric Blood and Cancer | 2007 | 4,018 |
| 86 | 5-Fluorouracil: mechanisms of action and clinical strategies | Nature Reviews Cancer | 2003 | 4,015 |
| 87 | Definition and classification of cancer cachexia: an international consensus | Lancet Oncology, The | 2011 | 4,015 |
| 88 | ras oncogenes in human cancer: a review | Cancer Research | 1989 | 3,985 |
| 89 | Fibroblasts in cancer | Nature Reviews Cancer | 2006 | 3,978 |
| 90 | Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European organization for research and treatment of cancer (EORTC) | International Journal of Radiation Oncology Biology Physics | 1995 | 3,975 |
| 91 | The resurgence of platinum-based cancer chemotherapy | Nature Reviews Cancer | 2007 | 3,971 |
| 92 | The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited | Nature Reviews Cancer | 2003 | 3,962 |
| 93 | The Eighth Edition AJCC Cancer Staging Manual: Continuing to build a bridge from a population‐based to a more “personalized” approach to cancer staging | Ca-A Cancer Journal for Clinicians | 2017 | 3,940 |
| 94 | Tolerance of normal tissue to therapeutic irradiation | International Journal of Radiation Oncology Biology Physics | 1991 | 3,929 |
| 95 | Photodynamic therapy of cancer: An update | Ca-A Cancer Journal for Clinicians | 2011 | 3,902 |
| 96 | One Hundred Years After “Carcinoid”: Epidemiology of and Prognostic Factors for Neuroendocrine Tumors in 35,825 Cases in the United States | Journal of Clinical Oncology | 2008 | 3,875 |
| 97 | The immune contexture in human tumours: impact on clinical outcome | Nature Reviews Cancer | 2012 | 3,873 |
| 98 | Radiomics: Extracting more information from medical images using advanced feature analysis | European Journal of Cancer | 2012 | 3,846 |
| 99 | Microtubules as a target for anticancer drugs | Nature Reviews Cancer | 2004 | 3,823 |
| 100 | Triple-Negative Breast Cancer: Clinical Features and Patterns of Recurrence | Clinical Cancer Research | 2007 | 3,807 |
